TROMA-III

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SKU: TROMA-III

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DSHB Data Sheet

Catalog Fields

Clone ID/Product Name: TROMA-III
Available to For-Profits: Yes
Alternate Antibody Name:
Gene Symbol: Krt19
Ab Isotype: RIgG2a, kappa light chain
Gene Name:
Antibody Registry ID: AB_2133570 
Uniprot ID: P19001 
RRID:  
Entrez Gene ID: 16669 
Clonality: Monoclonal
Immunogen: TDM1 (Trophoblastoma) cell line intermediate filaments
Clone:
Immunogen Sequence: Full length protein
Myeloma Strain: SP2/0
Epitope Mapped: No
Antigen Name: Keratin, type I; cytokeratin 19
Epitope Location or Sequence:
Alternate Antigen Name:
Deposit Date: 12/22/2004
Antigen Molecular Weight: Predicted: 44.5 kDa
Depositor: Kemler, R.
Antigen Sequence:
Depositor Institution: MPI fuer Immunobiologie
Antigen Species: Mouse
Depositor Notes: Methanol: acetone (1:1) fixation works well for cultured cells.
Host Species: rat
Hybridoma Cells Available (Non-Profit): Yes
Confirmed Species Reactivity: Human, Mouse, Rat
Additional Information: On paraffin sections, an antigen retrieval protocol using Tris-EDTA buffer pH 9.0 has been successful. PMID: 33847081.
Predicted Species Reactivity:  
Human Protein Atlas:  
Additional Characterization:  
Recommended Applications: FACS, FFPE, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
All cell products contain the antimicrobial ProClin. Click here for additional information.
These hybridomas were created by your colleagues. Please acknowledge the hybridoma contributor and the Developmental Studies Hybridoma Bank (DSHB) in the Materials and Methods of your publications. Please email the citation to us.
For your Materials & Methods section:
TROMA-III was deposited to the DSHB by Kemler, R. (DSHB Hybridoma Product TROMA-III)
Storage and Handling Recommendations
Although many cell products are maintained at 4°C for years without loss of activity, shelf-life at 4°C is highly variable. For immediate use, short term storage at 4°C up to two weeks is recommended. For long term storage, divide the solution into volumes of no less than 20 ul for freezing at -20°C or -80°C. The small volume aliquot should provide sufficient reagent for short term use. Freeze-thaw cycles should be avoided. For concentrate or bioreactor products, an equal volume of glycerol, a cryoprotectant, may be added prior to freezing.
Usage Recommendations
The optimal Ig concentration for an application varies by species and antibody affinity. For each product, the antibody titer must be optimized for every application by the end user laboratory. A good starting concentration for immunohistochemistry (IHC), immunofluorescence (IF), and immunocytochemistry (ICC) when using mouse Ig is 2-5 ug/ml. For western blots, the recommended concentration range of mouse Ig 0.2-0.5 ug/ml. In general, rabbit antibodies demonstrate greater affinity and are used at a magnitude lower Ig concentration for initial testing. The recommended concentrations for rabbit Ig are 0.2-0.5 ug/ml (IF, IHC and ICC) and 20-50 ng/ml (WB).

178 References

  • Initial Publication
  • IF References
  • WB References
  • IHC References
  • FFPE References
  • FACS References
  • All References
  • Initial Publication

    Monoclonal antibodies against trophectoderm-specific markers during mouse blastocyst formation.
    Jacob F
    Proceedings of the National Academy of Sciences of the United States of America 77.7 (1980 Jul): 4113-7.

    IF References

    Arid1a restrains Kras-dependent changes in acinar cell identity.
    Lowe SW
    eLife 7. (2018 Jul 17): .

    Glucocorticoids promote transition of ductal carcinoma in situ to invasive ductal carcinoma by inducing myoepithelial cell apoptosis.
    Fuster G
    Breast cancer research : BCR 20.1 (2018 Jul 4): 65.

    HMGB1 links chronic liver injury to progenitor responses and hepatocarcinogenesis.
    Schwabe RF
    The Journal of clinical investigation 128.6 (2018 Jun 1): 2436-2451.

    Aire-deficient mice provide a model of corneal and lacrimal gland neuropathy in Sjögren's syndrome.
    McNamara NA
    PloS one 12.9 (2017): e0184916.

    The Hippo signaling functions through the Notch signaling to regulate intrahepatic bile duct development in mammals.
    Bai H
    Laboratory investigation; a journal of technical methods and pathology 97.7 (2017 Jul): 843-853.

    Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis.
    Crawford HC
    Cellular and molecular gastroenterology and hepatology 3.1 (2017 Jan): 99-118.

    Hepatocyte specific expression of an oncogenic variant of β-catenin results in cholestatic liver disease.
    Österreicher CH
    Oncotarget 7.52 (2016 Dec 27): 86985-86998.

    Reg proteins promote acinar-to-ductal metaplasia and act as novel diagnostic and prognostic markers in pancreatic ductal adenocarcinoma.
    Gao ZH
    Oncotarget 7.47 (2016 Nov 22): 77838-77853.

    SOX2 regulates acinar cell development in the salivary gland.
    Knox SM
    eLife 6. (2017 Jun 17): .

    Genetic tracing of hepatocytes in liver homeostasis, injury, and regeneration.
    Zhou B
    The Journal of biological chemistry 292.21 (2017 May 26): 8594-8604.

    Cytoplasmic keratins couple with and maintain nuclear envelope integrity in colonic epithelial cells.
    Toivola DM
    Molecular biology of the cell 33.13 (2022 Nov 1): ar121.

    Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development.
    Kobayashi A
    Developmental cell 41.4 (2017 May 22): 349-365.e3.

    Ductular reaction correlates with fibrogenesis but does not contribute to liver regeneration in experimental fibrosis models.
    Dezső K
    PloS one 12.4 (2017): e0176518.

    Combined MEK and Pi3'-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo.
    Charles RP
    Oncotarget 8.15 (2017 Apr 11): 24604-24620.

    FGF21 Is an Exocrine Pancreas Secretagogue.
    Mangelsdorf DJ
    Cell metabolism 25.2 (2017 Feb 7): 472-480.

    Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration.
    Zhou B
    Nature communications 7. (2016 Nov 18): 13369.

    LKB1 loss links serine metabolism to DNA methylation and tumorigenesis.
    Bardeesy N
    Nature 539.7629 (2016 Nov 17): 390-395.

    Infliximab and Dexamethasone Attenuate the Ductular Reaction in Mice.
    van Grunsven LA
    Scientific reports 6. (2016 Nov 8): 36586.

    Macrophage Depletion Attenuates Extracellular Matrix Deposition and Ductular Reaction in a Mouse Model of Chronic Cholangiopathies.
    van Grunsven LA
    PloS one 11.9 (2016): e0162286.

    Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia.
    Ostrowski MC
    Neoplasia (New York, N.Y.) 18.9 (2016 Sep): 541-52.

    The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis through decreased glutathione and SOX17.
    Wells RG
    Hepatology (Baltimore, Md.) 64.3 (2016 Sep): 880-93.

    Transgenic Expression of a Single Transcription Factor Pdx1 Induces Transdifferentiation of Pancreatic Acinar Cells to Endocrine Cells in Adult Mice.
    Miyazaki J
    PloS one 11.8 (2016): e0161190.

    K14 + compound niches are present on the mouse cornea early after birth and expand after debridement wounds.
    Stepp MA
    Developmental dynamics : an official publication of the American Association of Anatomists 245.2 (2016 Feb): 132-43.

    Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma.
    Pikarsky E
    Nature immunology 16.12 (2015 Dec): 1235-44.

    Comparison of methods for the isolation of human breast epithelial and myoepithelial cells.
    Gascón P
    Frontiers in cell and developmental biology 3. (2015): 32.

    Activated macrophages create lineage-specific microenvironments for pancreatic acinar- and β-cell regeneration in mice.
    Esni F
    Gastroenterology 147.5 (2014 Nov): 1106-18.e11.

    The biliary epithelium gives rise to liver progenitor cells.
    Sancho-Bru P
    Hepatology (Baltimore, Md.) 60.4 (2014 Oct): 1367-77.

    Epiplakin deficiency aggravates murine caerulein-induced acute pancreatitis and favors the formation of acinar keratin granules.
    Fuchs P
    PloS one 9.9 (2014): e108323.

    Parasympathetic innervation regulates tubulogenesis in the developing salivary gland.
    Knox SM
    Developmental cell 30.4 (2014 Aug 25): 449-62.

    Tannic acid label indicates abnormal cell development coinciding with regeneration of renal tubules.
    Denk L
    BMC clinical pathology 14. (2014): 34.

    Age-related dysfunction in mechanotransduction impairs differentiation of human mammary epithelial progenitors.
    LaBarge MA
    Cell reports 7.6 (2014 Jun 26): 1926-39.

    Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma.
    Tournier C
    Cancer research 74.12 (2014 Jun 15): 3344-56.

    Fascin is regulated by slug, promotes progression of pancreatic cancer in mice, and is associated with patient outcomes.
    Machesky LM
    Gastroenterology 146.5 (2014 May): 1386-96.e1-17.

    MAPK signaling is required for dedifferentiation of acinar cells and development of pancreatic intraepithelial neoplasia in mice.
    Pasca di Magliano M
    Gastroenterology 146.3 (2014 Mar): 822-834.e7.

    Heparin-binding epidermal growth factor-like growth factor eliminates constraints on activated Kras to promote rapid onset of pancreatic neoplasia.
    Means AL
    Oncogene 33.7 (2014 Feb 13): 823-31.

    Microarray data reveal relationship between Jag1 and Ddr1 in mouse liver.
    Loomes KM
    PloS one 8.12 (2013): e84383.

    Pancreatic cancer-associated retinoblastoma 1 dysfunction enables TGF-β to promote proliferation.
    Korc M
    The Journal of clinical investigation 124.1 (2014 Jan): 338-52.

    Keratin 8 modulates β-cell stress responses and normoglycaemia.
    Toivola DM
    Journal of cell science 126.Pt 24 (2013 Dec 15): 5635-44.

    A novel role of nucleostemin in maintaining the genome integrity of dividing hepatocytes during mouse liver development and regeneration.
    Tsai RY
    Hepatology (Baltimore, Md.) 58.6 (2013 Dec): 2176-87.

    Novel pancreatic cancer cell lines derived from genetically engineered mouse models of spontaneous pancreatic adenocarcinoma: applications in diagnosis and therapy.
    Batra SK
    PloS one 8.11 (2013): e80580.

    Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology.
    Schwabe RF
    Nature communications 4. (2013): 2823.

    Isoprenylcysteine carboxylmethyltransferase deficiency exacerbates KRAS-driven pancreatic neoplasia via Notch suppression.
    Philips MR
    The Journal of clinical investigation 123.11 (2013 Nov): 4681-94.

    Interleukin-6 is required for pancreatic cancer progression by promoting MAPK signaling activation and oxidative stress resistance.
    di Magliano MP
    Cancer research 73.20 (2013 Oct 15): 6359-74.

    Aging phenotypes in cultured normal human mammary epithelial cells are correlated with decreased telomerase activity independent of telomere length.
    LaBarge MA
    Genome integrity 4.1 (2013 May 29): 4.

    Characterization of β-cell plasticity mechanisms induced in mice by a transient source of exogenous insulin.
    Guiot Y
    American journal of physiology. Endocrinology and metabolism 304.7 (2013 Apr 1): E711-23.

    Derivation and characterization of sleeping beauty transposon-mediated porcine induced pluripotent stem cells.
    Niemann H
    Stem cells and development 22.1 (2013 Jan 1): 124-35.

    Notch signaling differentially regulates the cell fate of early endocrine precursor cells and their maturing descendants in the mouse pancreas and intestine.
    Leiter AB
    Developmental biology 371.2 (2012 Nov 15): 156-69.

    Rotavirus infection of human cholangiocytes parallels the murine model of biliary atresia.
    Tiao G
    The Journal of surgical research 177.2 (2012 Oct): 275-81.

    c-Jun/AP-1 is required for CCK-induced pancreatic acinar cell dedifferentiation and DNA synthesis in vitro.
    Williams JA
    American journal of physiology. Gastrointestinal and liver physiology 302.12 (2012 Jun 15): G1381-96.

    Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia.
    Bar-Sagi D
    Cancer cell 21.6 (2012 Jun 12): 836-47.

    Protein kinase C iota regulates pancreatic acinar-to-ductal metaplasia.
    Murray NR
    PloS one 7.2 (2012): e30509.

    Secretin is not necessary for exocrine pancreatic development and growth in mice.
    Williams JA
    American journal of physiology. Gastrointestinal and liver physiology 301.5 (2011 Nov): G791-8.

    Energy determinants GAPDH and NDPK act as genetic modifiers for hepatocyte inclusion formation.
    Omary MB
    The Journal of cell biology 195.2 (2011 Oct 17): 217-29.

    Duct cells contribute to regeneration of endocrine and acinar cells following pancreatic damage in adult mice.
    Esni F
    Gastroenterology 141.4 (2011 Oct): 1451-62, 1462.e1-6.

    Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis.
    Wells RG
    Hepatology (Baltimore, Md.) 53.5 (2011 May): 1685-95.

    Paracrine modulation of cholangiocyte serotonin synthesis orchestrates biliary remodeling in adults.
    Diehl AM
    American journal of physiology. Gastrointestinal and liver physiology 300.2 (2011 Feb): G303-15.

    Absence of keratin 8 confers a paradoxical microflora-dependent resistance to apoptosis in the colon.
    Omary MB
    Proceedings of the National Academy of Sciences of the United States of America 108.4 (2011 Jan 25): 1445-50.

    Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome.
    Iruela-Arispe ML
    Development (Cambridge, England) 137.23 (2010 Dec): 4061-72.

    Pancreatic Duodenal Homeobox-1 de novo expression drives cholangiocyte neuroendocrine-like transdifferentiation.
    Benedetti A
    Journal of hepatology 53.4 (2010 Oct): 663-70.

    Genetic labeling does not detect epithelial-to-mesenchymal transition of cholangiocytes in liver fibrosis in mice.
    Kisseleva T
    Gastroenterology 139.3 (2010 Sep): 987-98.

    Gender dimorphic formation of mouse Mallory-Denk bodies and the role of xenobiotic metabolism and oxidative stress.
    Omary MB
    Gastroenterology 138.4 (2010 Apr): 1607-17.

    Cytokeratin expression during mouse embryonic and early postnatal mammary gland development.
    Dai X
    Histochemistry and cell biology 133.2 (2010 Feb): 213-21.

    DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration.
    Pezzano M
    PloS one 5.2 (2010 Feb 8): e9062.

    Cytokeratin expression during mouse embryonic and early postnatal mammary gland development.
    Dai X
    Histochemistry and cell biology 133.2 (2010 Feb): 213-21.

    Relation between liver progenitor cell expansion and extracellular matrix deposition in a CDE-induced murine model of chronic liver injury.
    Leclercq IA
    Hepatology (Baltimore, Md.) 49.5 (2009 May): 1625-35.

    Galectin-1 is a novel functional receptor for tissue plasminogen activator in pancreatic cancer.
    Navarro P
    Gastroenterology 136.4 (2009 Apr): 1379-90, e1-5.

    Human mammary progenitor cell fate decisions are products of interactions with combinatorial microenvironments.
    Bissell MJ
    Integrative biology : quantitative biosciences from nano to macro 1.1 (2009 Jan): 70-9.

    Dermal condensation formation in the chick embryo: requirement for integrin engagement and subsequent stabilization by a possible notch/integrin interaction.
    Dhouailly D
    Developmental dynamics : an official publication of the American Association of Anatomists 236.3 (2007 Mar): 755-68.

    Organ-specific stress induces mouse pancreatic keratin overexpression in association with NF-kappaB activation.
    Omary MB
    Journal of cell science 117.Pt 9 (2004 Apr 1): 1709-19.

    Monoclonal antibodies against trophectoderm-specific markers during mouse blastocyst formation.
    Jacob F
    Proceedings of the National Academy of Sciences of the United States of America 77.7 (1980 Jul): 4113-7.

    F-actin dynamics regulates mammalian organ growth and cell fate maintenance.
    Dupont S
    Journal of hepatology 71.1 (2019 Jul): 130-142.

    Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia.
    Labarge MA
    Cancer research 72.14 (2012 Jul 15): 3687-701.

    High-Dimensional Phenotyping Identifies Age-Emergent Cells in Human Mammary Epithelia.
    Lorens JB
    Cell reports 23.4 (2018 Apr 24): 1205-1219.

    Sesn3 deficiency promotes carcinogen-induced hepatocellular carcinoma via regulation of the hedgehog pathway.
    Dong XC
    Biochimica et biophysica acta. Molecular basis of disease 1865.10 (2019 Oct 1): 2685-2693.

    Chondrocyte-like nested cells in the aged intervertebral disc are late-stage nucleus pulposus cells.
    Dahia CL
    Aging cell 18.5 (2019 Oct): e13006.

    Macrophage phenotypic switch orchestrates the inflammation and repair/regeneration following acute pancreatitis injury.
    Xue J
    EBioMedicine 58. (2020 Aug): 102920.

    Defining a timeline of colon pathologies after keratin 8 loss: rapid crypt elongation and diarrhea are followed by epithelial erosion and cell exfoliation.
    Toivola DM
    American journal of physiology. Gastrointestinal and liver physiology 326.1 (2024 Jan 1): G67-G77.

    WB References

    Generation and characterisation of keratin 7 (K7) knockout mice.
    McLean WH
    PloS one 8.5 (2013): e64404.

    Akt and mTORC1 have different roles during liver tumorigenesis in mice.
    Yeung RS
    Gastroenterology 144.5 (2013 May): 1055-65.

    Energy determinants GAPDH and NDPK act as genetic modifiers for hepatocyte inclusion formation.
    Omary MB
    The Journal of cell biology 195.2 (2011 Oct 17): 217-29.

    Paracrine modulation of cholangiocyte serotonin synthesis orchestrates biliary remodeling in adults.
    Diehl AM
    American journal of physiology. Gastrointestinal and liver physiology 300.2 (2011 Feb): G303-15.

    Keratin hypersumoylation alters filament dynamics and is a marker for human liver disease and keratin mutation.
    Omary MB
    The Journal of biological chemistry 286.3 (2011 Jan 21): 2273-84.

    Tumor-initiating function of nucleostemin-enriched mammary tumor cells.
    Tsai RY
    Cancer research 70.22 (2010 Nov 15): 9444-52.

    Gender dimorphic formation of mouse Mallory-Denk bodies and the role of xenobiotic metabolism and oxidative stress.
    Omary MB
    Gastroenterology 138.4 (2010 Apr): 1607-17.

    Keratin variants are overrepresented in primary biliary cirrhosis and associate with disease severity.
    Omary MB
    Hepatology (Baltimore, Md.) 50.2 (2009 Aug): 546-54.

    Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2-/- mice.
    Trauner M
    Hepatology (Baltimore, Md.) 49.6 (2009 Jun): 1972-81.

    Organ-specific stress induces mouse pancreatic keratin overexpression in association with NF-kappaB activation.
    Omary MB
    Journal of cell science 117.Pt 9 (2004 Apr 1): 1709-19.

    Keratins modulate colonocyte electrolyte transport via protein mistargeting.
    Omary MB
    The Journal of cell biology 164.6 (2004 Mar 15): 911-21.

    Monoclonal antibodies against trophectoderm-specific markers during mouse blastocyst formation.
    Jacob F
    Proceedings of the National Academy of Sciences of the United States of America 77.7 (1980 Jul): 4113-7.

    Cytoplasmic keratins couple with and maintain nuclear envelope integrity in colonic epithelial cells.
    Toivola DM
    Molecular biology of the cell 33.13 (2022 Nov 1): ar121.

    Loss of luminal carbonic anhydrase XIV results in decreased biliary bicarbonate output, liver fibrosis, and cholangiocyte proliferation in mice.
    Seidler U
    Pflugers Archiv : European journal of physiology 474.5 (2022 May): 529-539.

    Defining a timeline of colon pathologies after keratin 8 loss: rapid crypt elongation and diarrhea are followed by epithelial erosion and cell exfoliation.
    Toivola DM
    American journal of physiology. Gastrointestinal and liver physiology 326.1 (2024 Jan 1): G67-G77.

    IHC References

    CDKN2B deletion is essential for pancreatic cancer development instead of unmeaningful co-deletion due to juxtaposition to CDKN2A.
    Zhao X
    Oncogene 37.1 (2018 Jan 4): 128-138.

    Dual role of protein tyrosine phosphatase 1B in the progression and reversion of non-alcoholic steatohepatitis.
    Valverde ÁM
    Molecular metabolism 7. (2018 Jan): 132-146.

    The Cholangiocyte Adenosine-IL-6 Axis Regulates Survival During Biliary Cirrhosis.
    Dranoff JA
    Gene expression 17.4 (2017 Nov 27): 327-340.

    Notch signaling and progenitor/ductular reaction in steatohepatitis.
    Strazzabosco M
    PloS one 12.11 (2017): e0187384.

    Duct- and Acinar-Derived Pancreatic Ductal Adenocarcinomas Show Distinct Tumor Progression and Marker Expression.
    Behrens A
    Cell reports 21.4 (2017 Oct 24): 966-978.

    Pdx1-Cre-driven conditional gene depletion suggests PAK4 as dispensable for mouse pancreas development.
    Strömblad S
    Scientific reports 7.1 (2017 Aug 1): 7031.

    Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis.
    Pasparakis M
    The Journal of clinical investigation 127.7 (2017 Jun 30): 2662-2677.

    NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma.
    Miller G
    The Journal of experimental medicine 214.6 (2017 Jun 5): 1711-1724.

    Expression and localization of sterile alpha motif domain containing 5 is associated with cell type and malignancy of biliary tree.
    Tanaka M
    PloS one 12.4 (2017): e0175355.

    Nlrp3 Activation Induces Il-18 Synthesis and Affects the Epithelial Barrier Function in Reactive Cholangiocytes.
    Marzioni M
    The American journal of pathology 187.2 (2017 Feb): 366-376.

    Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis.
    Crawford HC
    Cellular and molecular gastroenterology and hepatology 3.1 (2017 Jan): 99-118.

    Defining a timeline of colon pathologies after keratin 8 loss: rapid crypt elongation and diarrhea are followed by epithelial erosion and cell exfoliation.
    Toivola DM
    American journal of physiology. Gastrointestinal and liver physiology 326.1 (2024 Jan 1): G67-G77.

    Infliximab and Dexamethasone Attenuate the Ductular Reaction in Mice.
    van Grunsven LA
    Scientific reports 6. (2016 Nov 8): 36586.

    Keratins Are Altered in Intestinal Disease-Related Stress Responses.
    Toivola DM
    Cells 5.3 (2016 Sep 10): .

    Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia.
    Ostrowski MC
    Neoplasia (New York, N.Y.) 18.9 (2016 Sep): 541-52.

    Murine junctional adhesion molecules JAM-B and JAM-C mediate endothelial and stellate cell interactions during hepatic fibrosis.
    Christen U
    Cell adhesion & migration 10.4 (2016 Jul 3): 419-33.

    Divergent Inflammatory, Fibrogenic, and Liver Progenitor Cell Dynamics in Two Common Mouse Models of Chronic Liver Injury.
    Tirnitz-Parker JEE
    The American journal of pathology 186.7 (2016 Jul): 1762-1774.

    LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development.
    Lim DS
    Nature communications 7. (2016 Jun 30): 11961.

    Enhanced Steatosis and Fibrosis in Liver of Adult Offspring Exposed to Maternal High-Fat Diet.
    Brigstock DR
    Gene expression 17.1 (2016): 47-59.

    Radiation Therapy Induces Macrophages to Suppress T-Cell Responses Against Pancreatic Tumors in Mice.
    Miller G
    Gastroenterology 150.7 (2016 Jun): 1659-1672.e5.

    Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer.
    Sage J
    Genes & development 30.7 (2016 Apr 1): 772-85.

    Posttranslational regulation of polycystin-2 protein expression as a novel mechanism of cholangiocyte reaction and repair from biliary damage.
    Strazzabosco M
    Hepatology (Baltimore, Md.) 62.6 (2015 Dec): 1828-39.

    YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors.
    Tchorz JS
    Hepatology (Baltimore, Md.) 62.5 (2015 Nov): 1497-510.

    Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.
    Siveke JT
    Nature medicine 21.10 (2015 Oct): 1163-71.

    Activation-Induced Cytidine Deaminase Contributes to Pancreatic Tumorigenesis by Inducing Tumor-Related Gene Mutations.
    Chiba T
    Cancer research 75.16 (2015 Aug 15): 3292-301.

    Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing.
    Winslow MM
    Genes & development 29.14 (2015 Jul 15): 1576-85.

    Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning.
    Lamers WH
    Developmental biology 396.2 (2014 Dec 15): 201-13.

    PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice.
    Crawford HC
    Gastroenterology 147.6 (2014 Dec): 1405-16.e7.

    Death receptor-independent FADD signalling triggers hepatitis and hepatocellular carcinoma in mice with liver parenchymal cell-specific NEMO knockout.
    Pasparakis M
    Cell death and differentiation 21.11 (2014 Nov): 1721-32.

    Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma.
    Tournier C
    Cancer research 74.12 (2014 Jun 15): 3344-56.

    Inactivation of the transcription factor GLI1 accelerates pancreatic cancer progression.
    Fernandez-Zapico ME
    The Journal of biological chemistry 289.23 (2014 Jun 6): 16516-25.

    Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression.
    David G
    The Journal of clinical investigation 124.5 (2014 May): 2125-35.

    CD4+ T lymphocyte ablation prevents pancreatic carcinogenesis in mice.
    di Magliano MP
    Cancer immunology research 2.5 (2014 May): 423-35.

    Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells.
    Savatier P
    Nature communications 5. (2014 Apr 28): 3719.

    Loss of cilia causes embryonic lung hypoplasia, liver fibrosis, and cholestasis in the talpid3 ciliopathy mutant.
    Stephen LA
    Organogenesis 10.2 (2014 Apr-Jun): 177-85.

    Altered expression and function of canalicular transporters during early development of cholestatic liver injury in Abcb4-deficient mice.
    Boyer JL
    American journal of physiology. Gastrointestinal and liver physiology 306.8 (2014 Apr 15): G670-6.

    All-trans-retinoic acid improves cholestasis in α-naphthylisothiocyanate-treated rats and Mdr2-/- mice.
    Boyer JL
    The Journal of pharmacology and experimental therapeutics 349.1 (2014 Apr): 94-8.

    Polysialic acid/neural cell adhesion molecule modulates the formation of ductular reactions in liver injury.
    Forbes SJ
    Hepatology (Baltimore, Md.) 60.5 (2014 Nov): 1727-40.

    Heparin-binding epidermal growth factor-like growth factor eliminates constraints on activated Kras to promote rapid onset of pancreatic neoplasia.
    Means AL
    Oncogene 33.7 (2014 Feb 13): 823-31.

    Cholestasis induces reversible accumulation of periplakin in mouse liver.
    Gonzalez FJ
    BMC gastroenterology 13. (2013 Jul 13): 116.

    Akt and mTORC1 have different roles during liver tumorigenesis in mice.
    Yeung RS
    Gastroenterology 144.5 (2013 May): 1055-65.

    The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis.
    Rustgi AK
    Genes & development 27.3 (2013 Feb 1): 288-300.

    FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration.
    Miyajima A
    Genes & development 27.2 (2013 Jan 15): 169-81.

    Metastatic pancreatic cancer is dependent on oncogenic Kras in mice.
    di Magliano MP
    PloS one 7.12 (2012): e49707.

    Liver progenitor cells yield functional hepatocytes in response to chronic liver injury in mice.
    Leclercq IA
    Gastroenterology 143.6 (2012 Dec): 1564-1575.e7.

    A porcine model of familial adenomatous polyposis.
    Schnieke A
    Gastroenterology 143.5 (2012 Nov): 1173-1175.e7.

    Loss of CFTR affects biliary epithelium innate immunity and causes TLR4-NF-κB-mediated inflammatory response in mice.
    Strazzabosco M
    Gastroenterology 141.4 (2011 Oct): 1498-508, 1508.e1-5.

    Acute pancreatitis accelerates initiation and progression to pancreatic cancer in mice expressing oncogenic Kras in the nestin cell lineage.
    Korc M
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