81.5C10

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SKU: 81.5C10

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Available: 400

DSHB Data Sheet

Catalog Fields

Clone ID/Product Name: 81.5C10
Available to For-Profits: Yes
Alternate Antibody Name:
Gene Symbol: MNR2
Ab Isotype: MIgG1, kappa light chain
Gene Name:
Antibody Registry ID: AB_2145209 
Uniprot ID: Q9YHY8 
RRID:  
Entrez Gene ID: 395769 
Clonality: Monoclonal
Immunogen: MNR2 NH2(C-terminus; chick)-GST fusion protein expressed in E. coli.
Clone:
Immunogen Sequence:
Myeloma Strain: NS-1
Epitope Mapped: No
Antigen Name: MNR2/HB9/Mnx1
Epitope Location or Sequence:
Alternate Antigen Name:
Deposit Date: 2/12/1999
Antigen Molecular Weight:
Depositor: Jessell, T.M. / Brenner-Morton, S.
Antigen Sequence:
Depositor Institution: Columbia University / HHMI
Antigen Species: Chicken
Depositor Notes:
Host Species: mouse
Hybridoma Cells Available (Non-Profit): Yes
Confirmed Species Reactivity: Fish, Human, Mouse, Zebrafish
Additional Information: recognize Mnx1 (mouse, PMID: 25179941)
Predicted Species Reactivity:  
Human Protein Atlas:  
Additional Characterization:  
Recommended Applications: Immunofluorescence, Immunohistochemistry
All cell products contain the antimicrobial ProClin. Click here for additional information.
These hybridomas were created by your colleagues. Please acknowledge the hybridoma contributor and the Developmental Studies Hybridoma Bank (DSHB) in the Materials and Methods of your publications. Please email the citation to us.
For your Materials & Methods section:
81.5C10 was deposited to the DSHB by Jessell, T.M. / Brenner-Morton, S. (DSHB Hybridoma Product 81.5C10)
Storage and Handling Recommendations
Although many cell products are maintained at 4°C for years without loss of activity, shelf-life at 4°C is highly variable. For immediate use, short term storage at 4°C up to two weeks is recommended. For long term storage, divide the solution into volumes of no less than 20 ul for freezing at -20°C or -80°C. The small volume aliquot should provide sufficient reagent for short term use. Freeze-thaw cycles should be avoided. For concentrate or bioreactor products, an equal volume of glycerol, a cryoprotectant, may be added prior to freezing.
Usage Recommendations
The optimal Ig concentration for an application varies by species and antibody affinity. For each product, the antibody titer must be optimized for every application by the end user laboratory. A good starting concentration for immunohistochemistry (IHC), immunofluorescence (IF), and immunocytochemistry (ICC) when using mouse Ig is 2-5 ug/ml. For western blots, the recommended concentration range of mouse Ig 0.2-0.5 ug/ml. In general, rabbit antibodies demonstrate greater affinity and are used at a magnitude lower Ig concentration for initial testing. The recommended concentrations for rabbit Ig are 0.2-0.5 ug/ml (IF, IHC and ICC) and 20-50 ng/ml (WB).

54 References

  • Initial Publication
  • IF References
  • IHC References
  • Gel Supershift References
  • All References
  • Initial Publication
    IF References

    Specification of motor neuron identity by the MNR2 homeodomain protein.
    Jessell TM
    Cell 95.1 (1998 Oct 2): 67-80.

    Inhibition of Sirt1 promotes neural progenitors toward motoneuron differentiation from human embryonic stem cells.
    Deng M
    Biochemical and biophysical research communications 404.2 (2011 Jan 14): 610-4.

    ADAM10 negatively regulates neuronal differentiation during spinal cord development.
    Luo J
    PloS one 9.1 (2014): e84617.

    Transcriptome profiling of spinal muscular atrophy motor neurons derived from mouse embryonic stem cells.
    Butchbach ME
    PloS one 9.9 (2014): e106818.

    The basic helix-loop-helix factor olig2 is essential for the development of motoneuron and oligodendrocyte lineages.
    Nabeshima Y
    Current biology : CB 12.13 (2002 Jul 9): 1157-63.

    Distinct activities of Msx1 and Msx3 in dorsal neural tube development.
    Johnson JE
    Development (Cambridge, England) 131.5 (2004 Mar): 1017-28.

    Tulp3 is a critical repressor of mouse hedgehog signaling.
    Petkovich M
    Developmental dynamics : an official publication of the American Association of Anatomists 238.5 (2009 May): 1140-9.

    Small ubiquitin-like Modifier (SUMO) modification inhibits GLI2 protein transcriptional activity in vitro and in vivo.
    Wang B
    The Journal of biological chemistry 287.24 (2012 Jun 8): 20483-9.

    Restricted expression of classic cadherins in the spinal cord of the chicken embryo.
    Redies C
    Frontiers in neuroanatomy 8. (2014): 18.

    Neurotrophic requirements of human motor neurons defined using amplified and purified stem cell-derived cultures.
    Henderson CE
    PloS one 9.10 (2014): e110324.

    Combinatorial analysis of developmental cues efficiently converts human pluripotent stem cells into multiple neuronal subtypes.
    Nedelec S
    Nature biotechnology 33.1 (2015 Jan): 89-96.

    Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord.
    Xiang M
    Developmental dynamics : an official publication of the American Association of Anatomists 244.1 (2015 Jan): 86-97.

    GDP-bound Galphai2 regulates spinal motor neuron differentiation through interaction with GDE2.
    Sockanathan S
    Developmental biology 341.1 (2010 May 1): 213-21.

    ZPK/DLK, a mitogen-activated protein kinase kinase kinase, is a critical mediator of programmed cell death of motoneurons.
    Itoh T
    The Journal of neuroscience : the official journal of the Society for Neuroscience 31.20 (2011 May 18): 7223-8.

    Chondrolectin mediates growth cone interactions of motor axons with an intermediate target.
    Becker CG
    The Journal of neuroscience : the official journal of the Society for Neuroscience 32.13 (2012 Mar 28): 4426-39.

    Transplanted motoneurons derived from human induced pluripotent stem cells form functional connections with target muscle.
    Wu W
    Stem cell research 11.1 (2013 Jul): 529-39.

    Global gene expression profiling of somatic motor neuron populations with different vulnerability identify molecules and pathways of degeneration and protection.
    Isacson O
    Brain : a journal of neurology 133.Pt 8 (2010 Aug): 2313-30.

    Genome-wide analysis reveals that Smad3 and JMJD3 HDM co-activate the neural developmental program.
    Martínez-Balbás MA
    Development (Cambridge, England) 139.15 (2012 Aug): 2681-91.

    Hedgehog and retinoic acid signaling cooperate to promote motoneurogenesis in zebrafish.
    Chen JK
    Development (Cambridge, England) 138.23 (2011 Dec): 5113-9.

    Cytochrome p450 cyp26a1 alters spinal motor neuron subtype identity in differentiating embryonic stem cells.
    Gudas LJ
    The Journal of biological chemistry 288.40 (2013 Oct 4): 28801-13.

    Dynamic expression of the Onecut transcription factors HNF-6, OC-2 and OC-3 during spinal motor neuron development.
    Clotman F
    Neuroscience 165.1 (2010 Jan 13): 116-29.

    Elucidation of target muscle and detailed development of dorsal motor neurons in chick embryo spinal cord.
    Yaginuma H
    The Journal of comparative neurology 521.13 (2013 Sep 1): 2987-3002.

    Expression of delta-protocadherins in the spinal cord of the chicken embryo.
    Redies C
    The Journal of comparative neurology 520.7 (2012 May 1): 1509-31.

    Mutations in Traf3ip1 reveal defects in ciliogenesis, embryonic development, and altered cell size regulation.
    Yoder BK
    Developmental biology 360.1 (2011 Dec 1): 66-76.

    Receptor tyrosine phosphatase PTPγ is a regulator of spinal cord neurogenesis.
    Stoker AW
    Molecular and cellular neurosciences 46.2 (2011 Feb): 469-82.

    Complex interactions between genes controlling trafficking in primary cilia.
    Anderson KV
    Nature genetics 43.6 (2011 Jun): 547-53.

    Cell-specific actions of a human LHX3 gene enhancer during pituitary and spinal cord development.
    Rhodes SJ
    Molecular endocrinology (Baltimore, Md.) 27.12 (2013 Dec): 2013-27.

    Spatiotemporally restricted regulation of generic motor neuron programs by miR-196-mediated repression of Hoxb8.
    Kessel M
    Developmental biology 344.2 (2010 Aug 15): 857-68.

    Motoneuron replacement for reinnervation of skeletal muscle in adult rats.
    Thomas CK
    Journal of neuropathology and experimental neurology 71.10 (2012 Oct): 921-30.

    The Rose-comb mutation in chickens constitutes a structural rearrangement causing both altered comb morphology and defective sperm motility.
    Andersson L
    PLoS genetics 8.6 (2012 Jun): e1002775.

    Lesion-induced generation of interneuron cell types in specific dorsoventral domains in the spinal cord of adult zebrafish.
    Becker CG
    The Journal of comparative neurology 520.16 (2012 Nov 1): 3604-16.

    Rbfox3-regulated alternative splicing of Numb promotes neuronal differentiation during development.
    Kawamoto S
    The Journal of cell biology 200.4 (2013 Feb 18): 443-58.

    Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification.
    Clotman F
    Development (Cambridge, England) 139.17 (2012 Sep): 3109-19.

    Establishment of motor neuron-V3 interneuron progenitor domain boundary in ventral spinal cord requires Groucho-mediated transcriptional corepression.
    Stifani S
    PloS one 7.2 (2012): e31176.

    Differentiation of spinal motor neurons from pluripotent human stem cells.
    Zhang SC
    Nature protocols 4.9 (2009): 1295-304.

    Commissural axonal corridors instruct neuronal migration in the mouse spinal cord.
    Wilson SI
    Nature communications 6. (2015 May 11): 7028.

    Three Tctn proteins are functionally conserved in the regulation of neural tube patterning and Gli3 processing but not ciliogenesis and Hedgehog signaling in the mouse.
    Wang B
    Developmental biology 430.1 (2017 Oct 1): 156-165.

    Generation of Regionally Specific Neural Progenitor Cells (NPCs) and Neurons from Human Pluripotent Stem Cells (hPSCs).
    Brafman DA
    Methods in molecular biology (Clifton, N.J.) 1516. (2016): 121-144.

    Dlk1-Dio3 locus-derived lncRNAs perpetuate postmitotic motor neuron cell fate and subtype identity.
    Chen JA
    eLife 7. (2018 Oct 12): .

    Childhood amyotrophic lateral sclerosis caused by excess sphingolipid synthesis.
    Bönnemann CG
    Nature medicine 27.7 (2021 Jul): 1197-1204.

    Generation of region-specific and high-purity neurons from human feeder-free iPSCs.
    Okano H
    Neuroscience letters 746. (2021 Feb 16): 135676.

    Optimized Protocol to Generate Spinal Motor Neuron Cells from Induced Pluripotent Stem Cells from Charcot Marie Tooth Patients.
    Lia AS
    Brain sciences 10.7 (2020 Jun 27): .

    Generation of Motor Neurons from Human ESCs/iPSCs Using Sendai Virus Vectors.
    Inoue H
    Methods in molecular biology (Clifton, N.J.) 2352. (2021): 127-132.

    IHC References

    Specification of motor neuron identity by the MNR2 homeodomain protein.
    Jessell TM
    Cell 95.1 (1998 Oct 2): 67-80.

    ADAM10 negatively regulates neuronal differentiation during spinal cord development.
    Luo J
    PloS one 9.1 (2014): e84617.

    The basic helix-loop-helix factor olig2 is essential for the development of motoneuron and oligodendrocyte lineages.
    Nabeshima Y
    Current biology : CB 12.13 (2002 Jul 9): 1157-63.

    Genetic dissection of Gata2 selective functions during specification of V2 interneurons in the developing spinal cord.
    Nardelli J
    Developmental neurobiology 75.7 (2015 Jul): 721-37.

    LIM factor Lhx3 contributes to the specification of motor neuron and interneuron identity through cell-type-specific protein-protein interactions.
    Pfaff SL
    Cell 110.2 (2002 Jul 26): 237-49.

    Distinct activities of Msx1 and Msx3 in dorsal neural tube development.
    Johnson JE
    Development (Cambridge, England) 131.5 (2004 Mar): 1017-28.

    A functional study of miR-124 in the developing neural tube.
    Gage FH
    Genes & development 21.5 (2007 Mar 1): 531-6.

    Tulp3 is a critical repressor of mouse hedgehog signaling.
    Petkovich M
    Developmental dynamics : an official publication of the American Association of Anatomists 238.5 (2009 May): 1140-9.

    Role of motoneuron-derived neurotrophin 3 in survival and axonal projection of sensory neurons during neural circuit formation.
    Takebayashi H
    Development (Cambridge, England) 139.6 (2012 Mar): 1125-32.

    Small ubiquitin-like Modifier (SUMO) modification inhibits GLI2 protein transcriptional activity in vitro and in vivo.
    Wang B
    The Journal of biological chemistry 287.24 (2012 Jun 8): 20483-9.

    Restricted expression of classic cadherins in the spinal cord of the chicken embryo.
    Redies C
    Frontiers in neuroanatomy 8. (2014): 18.

    Intermediate filament protein accumulation in motor neurons derived from giant axonal neuropathy iPSCs rescued by restoration of gigaxonin.
    Wichterle H
    Human molecular genetics 24.5 (2015 Mar 1): 1420-31.

    Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord.
    Xiang M
    Developmental dynamics : an official publication of the American Association of Anatomists 244.1 (2015 Jan): 86-97.

    GDP-bound Galphai2 regulates spinal motor neuron differentiation through interaction with GDE2.
    Sockanathan S
    Developmental biology 341.1 (2010 May 1): 213-21.

    ZPK/DLK, a mitogen-activated protein kinase kinase kinase, is a critical mediator of programmed cell death of motoneurons.
    Itoh T
    The Journal of neuroscience : the official journal of the Society for Neuroscience 31.20 (2011 May 18): 7223-8.

    Chondrolectin mediates growth cone interactions of motor axons with an intermediate target.
    Becker CG
    The Journal of neuroscience : the official journal of the Society for Neuroscience 32.13 (2012 Mar 28): 4426-39.

    Transplanted motoneurons derived from human induced pluripotent stem cells form functional connections with target muscle.
    Wu W
    Stem cell research 11.1 (2013 Jul): 529-39.

    The transcription factors Nkx2.2 and Nkx2.9 play a novel role in floor plate development and commissural axon guidance.
    Arnold HH
    Development (Cambridge, England) 137.24 (2010 Dec): 4249-60.

    Genome-wide analysis reveals that Smad3 and JMJD3 HDM co-activate the neural developmental program.
    Martínez-Balbás MA
    Development (Cambridge, England) 139.15 (2012 Aug): 2681-91.

    Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube.
    Anderson KV
    Development (Cambridge, England) 138.22 (2011 Nov): 4921-30.

    Hedgehog and retinoic acid signaling cooperate to promote motoneurogenesis in zebrafish.
    Chen JK
    Development (Cambridge, England) 138.23 (2011 Dec): 5113-9.

    Elucidation of target muscle and detailed development of dorsal motor neurons in chick embryo spinal cord.
    Yaginuma H
    The Journal of comparative neurology 521.13 (2013 Sep 1): 2987-3002.

    Expression of delta-protocadherins in the spinal cord of the chicken embryo.
    Redies C
    The Journal of comparative neurology 520.7 (2012 May 1): 1509-31.

    Mutations in Traf3ip1 reveal defects in ciliogenesis, embryonic development, and altered cell size regulation.
    Yoder BK
    Developmental biology 360.1 (2011 Dec 1): 66-76.

    Receptor tyrosine phosphatase PTPγ is a regulator of spinal cord neurogenesis.
    Stoker AW
    Molecular and cellular neurosciences 46.2 (2011 Feb): 469-82.

    Complex interactions between genes controlling trafficking in primary cilia.
    Anderson KV
    Nature genetics 43.6 (2011 Jun): 547-53.

    Cell-specific actions of a human LHX3 gene enhancer during pituitary and spinal cord development.
    Rhodes SJ
    Molecular endocrinology (Baltimore, Md.) 27.12 (2013 Dec): 2013-27.

    Spatiotemporally restricted regulation of generic motor neuron programs by miR-196-mediated repression of Hoxb8.
    Kessel M
    Developmental biology 344.2 (2010 Aug 15): 857-68.

    The Rose-comb mutation in chickens constitutes a structural rearrangement causing both altered comb morphology and defective sperm motility.
    Andersson L
    PLoS genetics 8.6 (2012 Jun): e1002775.

    Lesion-induced generation of interneuron cell types in specific dorsoventral domains in the spinal cord of adult zebrafish.
    Becker CG
    The Journal of comparative neurology 520.16 (2012 Nov 1): 3604-16.

    Rbfox3-regulated alternative splicing of Numb promotes neuronal differentiation during development.
    Kawamoto S
    The Journal of cell biology 200.4 (2013 Feb 18): 443-58.

    Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification.
    Clotman F
    Development (Cambridge, England) 139.17 (2012 Sep): 3109-19.

    Establishment of motor neuron-V3 interneuron progenitor domain boundary in ventral spinal cord requires Groucho-mediated transcriptional corepression.
    Stifani S
    PloS one 7.2 (2012): e31176.

    Proliferation and recapitulation of developmental patterning associated with regulative regeneration of the spinal cord neural tube.
    Glover JC
    Developmental biology 365.1 (2012 May 1): 118-32.

    ARL13B regulates Sonic hedgehog signaling from outside primary cilia.
    Caspary T
    eLife 9. (2020 Mar 4): .

    Ddx20, an Olig2 binding factor, governs the survival of neural and oligodendrocyte progenitor cells via proper Mdm2 splicing and p53 suppression.
    Takebayashi H
    Cell death and differentiation 29.5 (2022 May): 1028-1041.

    Gel Supershift References
    All References

    Specification of motor neuron identity by the MNR2 homeodomain protein.
    Jessell TM
    Cell 95.1 (1998 Oct 2): 67-80.

    ADAM10 negatively regulates neuronal differentiation during spinal cord development.
    Luo J
    PloS one 9.1 (2014): e84617.

    The basic helix-loop-helix factor olig2 is essential for the development of motoneuron and oligodendrocyte lineages.
    Nabeshima Y
    Current biology : CB 12.13 (2002 Jul 9): 1157-63.

    Genetic dissection of Gata2 selective functions during specification of V2 interneurons in the developing spinal cord.
    Nardelli J
    Developmental neurobiology 75.7 (2015 Jul): 721-37.

    LIM factor Lhx3 contributes to the specification of motor neuron and interneuron identity through cell-type-specific protein-protein interactions.
    Pfaff SL
    Cell 110.2 (2002 Jul 26): 237-49.

    Distinct activities of Msx1 and Msx3 in dorsal neural tube development.
    Johnson JE
    Development (Cambridge, England) 131.5 (2004 Mar): 1017-28.

    A functional study of miR-124 in the developing neural tube.
    Gage FH
    Genes & development 21.5 (2007 Mar 1): 531-6.

    Tulp3 is a critical repressor of mouse hedgehog signaling.
    Petkovich M
    Developmental dynamics : an official publication of the American Association of Anatomists 238.5 (2009 May): 1140-9.

    Role of motoneuron-derived neurotrophin 3 in survival and axonal projection of sensory neurons during neural circuit formation.
    Takebayashi H
    Development (Cambridge, England) 139.6 (2012 Mar): 1125-32.

    Small ubiquitin-like Modifier (SUMO) modification inhibits GLI2 protein transcriptional activity in vitro and in vivo.
    Wang B
    The Journal of biological chemistry 287.24 (2012 Jun 8): 20483-9.

    Restricted expression of classic cadherins in the spinal cord of the chicken embryo.
    Redies C
    Frontiers in neuroanatomy 8. (2014): 18.

    Intermediate filament protein accumulation in motor neurons derived from giant axonal neuropathy iPSCs rescued by restoration of gigaxonin.
    Wichterle H
    Human molecular genetics 24.5 (2015 Mar 1): 1420-31.

    Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord.
    Xiang M
    Developmental dynamics : an official publication of the American Association of Anatomists 244.1 (2015 Jan): 86-97.

    GDP-bound Galphai2 regulates spinal motor neuron differentiation through interaction with GDE2.
    Sockanathan S
    Developmental biology 341.1 (2010 May 1): 213-21.

    ZPK/DLK, a mitogen-activated protein kinase kinase kinase, is a critical mediator of programmed cell death of motoneurons.
    Itoh T
    The Journal of neuroscience : the official journal of the Society for Neuroscience 31.20 (2011 May 18): 7223-8.

    Chondrolectin mediates growth cone interactions of motor axons with an intermediate target.
    Becker CG
    The Journal of neuroscience : the official journal of the Society for Neuroscience 32.13 (2012 Mar 28): 4426-39.

    Transplanted motoneurons derived from human induced pluripotent stem cells form functional connections with target muscle.
    Wu W
    Stem cell research 11.1 (2013 Jul): 529-39.

    The transcription factors Nkx2.2 and Nkx2.9 play a novel role in floor plate development and commissural axon guidance.
    Arnold HH
    Development (Cambridge, England) 137.24 (2010 Dec): 4249-60.

    Genome-wide analysis reveals that Smad3 and JMJD3 HDM co-activate the neural developmental program.
    Martínez-Balbás MA
    Development (Cambridge, England) 139.15 (2012 Aug): 2681-91.

    Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube.
    Anderson KV
    Development (Cambridge, England) 138.22 (2011 Nov): 4921-30.

    Hedgehog and retinoic acid signaling cooperate to promote motoneurogenesis in zebrafish.
    Chen JK
    Development (Cambridge, England) 138.23 (2011 Dec): 5113-9.

    Elucidation of target muscle and detailed development of dorsal motor neurons in chick embryo spinal cord.
    Yaginuma H
    The Journal of comparative neurology 521.13 (2013 Sep 1): 2987-3002.

    Expression of delta-protocadherins in the spinal cord of the chicken embryo.
    Redies C
    The Journal of comparative neurology 520.7 (2012 May 1): 1509-31.

    Mutations in Traf3ip1 reveal defects in ciliogenesis, embryonic development, and altered cell size regulation.
    Yoder BK
    Developmental biology 360.1 (2011 Dec 1): 66-76.

    Receptor tyrosine phosphatase PTPγ is a regulator of spinal cord neurogenesis.
    Stoker AW
    Molecular and cellular neurosciences 46.2 (2011 Feb): 469-82.

    Complex interactions between genes controlling trafficking in primary cilia.
    Anderson KV
    Nature genetics 43.6 (2011 Jun): 547-53.

    Cell-specific actions of a human LHX3 gene enhancer during pituitary and spinal cord development.
    Rhodes SJ
    Molecular endocrinology (Baltimore, Md.) 27.12 (2013 Dec): 2013-27.

    Spatiotemporally restricted regulation of generic motor neuron programs by miR-196-mediated repression of Hoxb8.
    Kessel M
    Developmental biology 344.2 (2010 Aug 15): 857-68.

    The Rose-comb mutation in chickens constitutes a structural rearrangement causing both altered comb morphology and defective sperm motility.
    Andersson L
    PLoS genetics 8.6 (2012 Jun): e1002775.

    Lesion-induced generation of interneuron cell types in specific dorsoventral domains in the spinal cord of adult zebrafish.
    Becker CG
    The Journal of comparative neurology 520.16 (2012 Nov 1): 3604-16.

    Rbfox3-regulated alternative splicing of Numb promotes neuronal differentiation during development.
    Kawamoto S
    The Journal of cell biology 200.4 (2013 Feb 18): 443-58.

    Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification.
    Clotman F
    Development (Cambridge, England) 139.17 (2012 Sep): 3109-19.

    Establishment of motor neuron-V3 interneuron progenitor domain boundary in ventral spinal cord requires Groucho-mediated transcriptional corepression.
    Stifani S
    PloS one 7.2 (2012): e31176.

    Proliferation and recapitulation of developmental patterning associated with regulative regeneration of the spinal cord neural tube.
    Glover JC
    Developmental biology 365.1 (2012 May 1): 118-32.

    ARL13B regulates Sonic hedgehog signaling from outside primary cilia.
    Caspary T
    eLife 9. (2020 Mar 4): .

    Ddx20, an Olig2 binding factor, governs the survival of neural and oligodendrocyte progenitor cells via proper Mdm2 splicing and p53 suppression.
    Takebayashi H
    Cell death and differentiation 29.5 (2022 May): 1028-1041.

    Inhibition of Sirt1 promotes neural progenitors toward motoneuron differentiation from human embryonic stem cells.
    Deng M
    Biochemical and biophysical research communications 404.2 (2011 Jan 14): 610-4.

    Transcriptome profiling of spinal muscular atrophy motor neurons derived from mouse embryonic stem cells.
    Butchbach ME
    PloS one 9.9 (2014): e106818.

    Neurotrophic requirements of human motor neurons defined using amplified and purified stem cell-derived cultures.
    Henderson CE
    PloS one 9.10 (2014): e110324.

    Combinatorial analysis of developmental cues efficiently converts human pluripotent stem cells into multiple neuronal subtypes.
    Nedelec S
    Nature biotechnology 33.1 (2015 Jan): 89-96.

    Global gene expression profiling of somatic motor neuron populations with different vulnerability identify molecules and pathways of degeneration and protection.
    Isacson O
    Brain : a journal of neurology 133.Pt 8 (2010 Aug): 2313-30.

    Cytochrome p450 cyp26a1 alters spinal motor neuron subtype identity in differentiating embryonic stem cells.
    Gudas LJ
    The Journal of biological chemistry 288.40 (2013 Oct 4): 28801-13.

    Dynamic expression of the Onecut transcription factors HNF-6, OC-2 and OC-3 during spinal motor neuron development.
    Clotman F
    Neuroscience 165.1 (2010 Jan 13): 116-29.

    Motoneuron replacement for reinnervation of skeletal muscle in adult rats.
    Thomas CK
    Journal of neuropathology and experimental neurology 71.10 (2012 Oct): 921-30.

    Differentiation of spinal motor neurons from pluripotent human stem cells.
    Zhang SC
    Nature protocols 4.9 (2009): 1295-304.

    Commissural axonal corridors instruct neuronal migration in the mouse spinal cord.
    Wilson SI
    Nature communications 6. (2015 May 11): 7028.

    Three Tctn proteins are functionally conserved in the regulation of neural tube patterning and Gli3 processing but not ciliogenesis and Hedgehog signaling in the mouse.
    Wang B
    Developmental biology 430.1 (2017 Oct 1): 156-165.

    Generation of Regionally Specific Neural Progenitor Cells (NPCs) and Neurons from Human Pluripotent Stem Cells (hPSCs).
    Brafman DA
    Methods in molecular biology (Clifton, N.J.) 1516. (2016): 121-144.

    Dlk1-Dio3 locus-derived lncRNAs perpetuate postmitotic motor neuron cell fate and subtype identity.
    Chen JA
    eLife 7. (2018 Oct 12): .

    Childhood amyotrophic lateral sclerosis caused by excess sphingolipid synthesis.
    Bönnemann CG
    Nature medicine 27.7 (2021 Jul): 1197-1204.

    Generation of region-specific and high-purity neurons from human feeder-free iPSCs.
    Okano H
    Neuroscience letters 746. (2021 Feb 16): 135676.

    Optimized Protocol to Generate Spinal Motor Neuron Cells from Induced Pluripotent Stem Cells from Charcot Marie Tooth Patients.
    Lia AS
    Brain sciences 10.7 (2020 Jun 27): .

    Generation of Motor Neurons from Human ESCs/iPSCs Using Sendai Virus Vectors.
    Inoue H
    Methods in molecular biology (Clifton, N.J.) 2352. (2021): 127-132.

    Characterization of an apparently novel β-cell line-enriched 80-88 kDa transcriptional activator of the MafA and Pdx1 genes.
    Stein R
    The Journal of biological chemistry 288.6 (2013 Feb 8): 3795-803.

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