anti-Acj6

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SKU: anti-Acj6

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DSHB Data Sheet

Catalog Fields

Clone ID/Product Name: anti-Acj6
Available to For-Profits: Yes
Alternate Antibody Name:
Gene Symbol: acj6
Ab Isotype: MIgG2a, kappa light chain
Gene Name:
Antibody Registry ID: AB_528067 
Uniprot ID: P24350 
RRID:  
Entrez Gene ID: 47080 
Clonality: Monoclonal
Immunogen: GST-Acj6 fusion protein
Clone:
Immunogen Sequence: a.a. 108-237
Myeloma Strain: NS1
Epitope Mapped: No
Antigen Name: Abnormal chemosensory jump 6/ Inhibitory POU protein
Epitope Location or Sequence:
Alternate Antigen Name:
Deposit Date: 5/30/2003
Antigen Molecular Weight: 43.7 kDa
Depositor: Johnson, W.A.
Antigen Sequence:
Depositor Institution: University of Iowa
Antigen Species: Drosophila
Depositor Notes: This antibody recognizes a molecular marker which identifies the ALad1 and LALv1 lineage as well as ALl1-derived interneurons (PMID: 25546307).
Host Species: mouse
Hybridoma Cells Available (Non-Profit): Yes
Confirmed Species Reactivity: Drosophila
Additional Information: RRID: AB_528067 FBgn0000028.
Predicted Species Reactivity:  
Human Protein Atlas:  
Additional Characterization:  
Recommended Applications: Immunofluorescence, Immunohistochemistry, Western Blot
All cell products contain the antimicrobial ProClin. Click here for additional information.
These hybridomas were created by your colleagues. Please acknowledge the hybridoma contributor and the Developmental Studies Hybridoma Bank (DSHB) in the Materials and Methods of your publications. Please email the citation to us.
For your Materials & Methods section:
anti-Acj6 was deposited to the DSHB by Johnson, W.A. (DSHB Hybridoma Product anti-Acj6)
Storage and Handling Recommendations
Although many cell products are maintained at 4°C for years without loss of activity, shelf-life at 4°C is highly variable. For immediate use, short term storage at 4°C up to two weeks is recommended. For long term storage, divide the solution into volumes of no less than 20 ul for freezing at -20°C or -80°C. The small volume aliquot should provide sufficient reagent for short term use. Freeze-thaw cycles should be avoided. For concentrate or bioreactor products, an equal volume of glycerol, a cryoprotectant, may be added prior to freezing.
Usage Recommendations
The optimal Ig concentration for an application varies by species and antibody affinity. For each product, the antibody titer must be optimized for every application by the end user laboratory. A good starting concentration for immunohistochemistry (IHC), immunofluorescence (IF), and immunocytochemistry (ICC) when using mouse Ig is 2-5 ug/ml. For western blots, the recommended concentration range of mouse Ig 0.2-0.5 ug/ml. In general, rabbit antibodies demonstrate greater affinity and are used at a magnitude lower Ig concentration for initial testing. The recommended concentrations for rabbit Ig are 0.2-0.5 ug/ml (IF, IHC and ICC) and 20-50 ng/ml (WB).

13 References

  • Initial Publication
  • IF References
  • IHC References
  • All References
  • Initial Publication
    IF References

    The odor specificities of a subset of olfactory receptor neurons are governed by Acj6, a POU-domain transcription factor.
    Carlson JR
    Neuron 22.2 (1999 Feb): 339-47.

    Empty spiracles is required for the development of olfactory projection neuron circuitry in Drosophila.
    Reichert H
    Development (Cambridge, England) 135.14 (2008 Aug): 2415-24.

    Engrailed expression in subsets of adult Drosophila sensory neurons: an enhancer-trap study.
    Blagburn JM
    Invertebrate neuroscience : IN 8.3 (2008 Sep): 133-46.

    Lineage-specific effects of Notch/Numb signaling in post-embryonic development of the Drosophila brain.
    Lee T
    Development (Cambridge, England) 137.1 (2010 Jan): 43-51.

    The Q system: a repressible binary system for transgene expression, lineage tracing, and mosaic analysis.
    Luo L
    Cell 141.3 (2010 Apr 30): 536-48.

    Hierarchical deployment of factors regulating temporal fate in a diverse neuronal lineage of the Drosophila central brain.
    Lee T
    Neuron 73.4 (2012 Feb 23): 677-84.

    Combinatorial activation and repression by seven transcription factors specify Drosophila odorant receptor expression.
    Alenius M
    PLoS biology 10.3 (2012): e1001280.

    The sox gene Dichaete is expressed in local interneurons and functions in development of the Drosophila adult olfactory circuit.
    Nambu JR
    Developmental neurobiology 73.2 (2013 Feb): 107-26.

    Neurogenic role of Gcm transcription factors is conserved in chicken spinal cord.
    Giangrande A
    Development (Cambridge, England) 134.3 (2007 Feb): 625-34.

    Notch regulates the generation of diverse cell types from the lateral lineage of Drosophila antennal lobe.
    Rodrigues V
    Journal of neurogenetics 24.1 (2010 Mar): 42-53.

    Nerfin-1 is required for early axon guidance decisions in the developing Drosophila CNS.
    Odenwald WF
    Developmental biology 277.2 (2005 Jan 15): 347-65.

    Hierarchical deployment of factors regulating temporal fate in a diverse neuronal lineage of the Drosophila central brain.
    Lee T
    Neuron 73.4 (2012 Feb 23): 677-84.

    Lola regulates Drosophila olfactory projection neuron identity and targeting specificity.
    Luo L
    Neural development 2. (2007 Jul 16): 14.

    The transcription factor SoxD controls neuronal guidance in the Drosophila visual system.
    Oliva C
    Scientific reports 8.1 (2018 Sep 6): 13332.

    IHC References
    All References

    The odor specificities of a subset of olfactory receptor neurons are governed by Acj6, a POU-domain transcription factor.
    Carlson JR
    Neuron 22.2 (1999 Feb): 339-47.

    Empty spiracles is required for the development of olfactory projection neuron circuitry in Drosophila.
    Reichert H
    Development (Cambridge, England) 135.14 (2008 Aug): 2415-24.

    Engrailed expression in subsets of adult Drosophila sensory neurons: an enhancer-trap study.
    Blagburn JM
    Invertebrate neuroscience : IN 8.3 (2008 Sep): 133-46.

    Lineage-specific effects of Notch/Numb signaling in post-embryonic development of the Drosophila brain.
    Lee T
    Development (Cambridge, England) 137.1 (2010 Jan): 43-51.

    The Q system: a repressible binary system for transgene expression, lineage tracing, and mosaic analysis.
    Luo L
    Cell 141.3 (2010 Apr 30): 536-48.

    Hierarchical deployment of factors regulating temporal fate in a diverse neuronal lineage of the Drosophila central brain.
    Lee T
    Neuron 73.4 (2012 Feb 23): 677-84.

    Combinatorial activation and repression by seven transcription factors specify Drosophila odorant receptor expression.
    Alenius M
    PLoS biology 10.3 (2012): e1001280.

    The sox gene Dichaete is expressed in local interneurons and functions in development of the Drosophila adult olfactory circuit.
    Nambu JR
    Developmental neurobiology 73.2 (2013 Feb): 107-26.

    Neurogenic role of Gcm transcription factors is conserved in chicken spinal cord.
    Giangrande A
    Development (Cambridge, England) 134.3 (2007 Feb): 625-34.

    Notch regulates the generation of diverse cell types from the lateral lineage of Drosophila antennal lobe.
    Rodrigues V
    Journal of neurogenetics 24.1 (2010 Mar): 42-53.

    Nerfin-1 is required for early axon guidance decisions in the developing Drosophila CNS.
    Odenwald WF
    Developmental biology 277.2 (2005 Jan 15): 347-65.

    Lola regulates Drosophila olfactory projection neuron identity and targeting specificity.
    Luo L
    Neural development 2. (2007 Jul 16): 14.

    The transcription factor SoxD controls neuronal guidance in the Drosophila visual system.
    Oliva C
    Scientific reports 8.1 (2018 Sep 6): 13332.

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